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KMID : 0379119800080020115
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Korean Journal of Mycology
1980 Volume.8 No. 2 p.115 ~ p.116
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Studies on Constituents and Culture of the Higher Fungi of Korea (25)
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Abstract
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To investigate mechanism of antineoplastic activities of the protein-polysaccharide fraction of Coriolus versicolor (Fr.) Quel, the mycelium of the fungus was grown in a liquid. medium and was extracted with hot water. The extract was purified and used for examining its effects upon immune response in mice. The fraction was administered at a dose of 20㎎/㎏/day to ICR mice for five days. After ten days the mice were immunized by sheep red blood cells. The plaque-forming cells (PFC) in their spleen were increased in the treated mice. The number of PFC in case of the protein-removed polysaccharide was lower than ´that of the entire protein-polysaccharide fraction of the fungus.
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